--- title: "Sustanon Injections Guide | The Gender Hormone Clinic" description: "A blend of four testosterone esters delivered by intramuscular injection every 3 weeks." url: https://thegenderhormoneclinic.com/patient-resources/medication-guides/sustanon-injections/ --- [Home](https://thegenderhormoneclinic.com/) / [Medication guides](https://thegenderhormoneclinic.com/patient-resources/medication-guides/) / Sustanon Injections TRANS-MASCULINE HRT · MEDICATION GUIDE # Sustanon Injections therapy, a clear guide. Sustanon is one of two main long-acting testosterone injections we prescribe. Compared with Nebido, doses are smaller and more frequent, and serum levels rise and fall more visibly between shots. Some patients prefer this rhythm, others prefer the steadier curve of Nebido. [Begin your journey](https://thegenderhormoneclinic.com/make-an-enquiry/) [See payment plans](https://thegenderhormoneclinic.com/patient-resources/payment-plans/) Drug class Androgen / testosterone ester blend Route Intramuscular Frequency Every 2-3 weeks Trough target 8-12 nmol/L testosterone Self-administration Permitted with training Dose 250 mg per injection (typical) On this page[Overview](#ma-overview)[Side effects](#ma-side-effects)[Cost](#ma-cost)[FAQ](#ma-faq) OVERVIEW ## What sustanon injections does, in plain English. Sustanon contains four testosterone esters in a single oil-based injection, designed to release testosterone over 2-3 weeks. It's well-established, widely available, and one of the few injectable hormones at GHC that you can be trained to self-administer at home. Drawing blood for monitoring is done immediately before your next scheduled dose. This gives the trough level we use for adjustments. SIDE EFFECTS & RISKS ## What to watch for, and what to tell us. Most patients tolerate Sustanon well. The peaks and troughs between doses are the most common driver of mood, energy, and libido fluctuations. Common Peaks and troughs + Mood, energy, libido, and acne can fluctuate between doses, more pronounced than with Nebido. Switching to weekly subcutaneous testosterone or Nebido often resolves it. Acne and skin changes + Especially in the first year. Usually settles. Injection-site soreness + For 24-48 hours after injection. Rotate sites. Voice deepening + Permanent. Begins around 3 months. Less common / serious Polycythaemia + Raised haematocrit (thicker blood). Monitored every 6 months. If it rises above safe limits we adjust the dose or switch route. Sleep apnoea + Testosterone can worsen pre-existing sleep apnoea. Tell us if you snore heavily. Monitoring schedule We catch things early. Here's the routine you can expect. Most of the testing is front-loaded while we fine-tune your dose. Once your levels are stable, it's usually just once a year. Baseline Full hormone panel FBC, U&E, LFTs Blood pressure 3–6 months Testosterone trough FBC (haematocrit) LFTs 6-monthly while adjusting Trough testosterone FBC, LFTs Lipids Yearly once stable Full panel BP, weight Symptom review COST ## What sustanon injections costs you, monthly. Sustanon is among the more affordable injectable testosterones. Once your GP enters NHS shared care, costs drop to the standard NHS prescription charge. Sustanon (private) £6-£8 per dose 1 dose every ~3 weeks Once on shared care £9.90 per item Standard NHS Rx charge [See full payment plan](https://thegenderhormoneclinic.com/patient-resources/payment-plans/) FREQUENTLY ASKED ## Questions, answered. This guide isn't a substitute for clinical advice. We'll talk you through everything at your appointment. [Make an enquiry](https://thegenderhormoneclinic.com/make-an-enquiry/) ## Ready to take the first step? Send us an enquiry and we'll be in touch within two working days. [Make an enquiry](https://thegenderhormoneclinic.com/make-an-enquiry/)